The DEPOWA National Secretariat carries out the diverse day-to-day works of the Association. It administers the programmes and policies of the Association. It also coordinates the activities at the National and Tri-Service levels.
The wife of the serving Chief of Defence Staff is always the President. The office of President, DEPOWA is located at the DEPOWA Secretariat, No. 1 Dame Patience Goodluck Jonathan, Road, Behind Command Guest House, Asokoro, Abuja.
Furthermore, some members of the Association are appointed or elected to form the Executive Officers. The officials are:
- The Vice President (the wife of the next in command to the Chief of Defence Staff should be the Vice President).
- General Secretary
- Assistant General Secretary
- Financial Secretary
- Social Secretary
- Assistant Social secretary
- Publicity Secretary
- Assistant Publicity Secretary
- Legal Adviser
The Secretariat has the ultra modern conference Hall and other offices.